ME - What it IS…

ME stands for Myalgic Encephalomyelitis.
Myalgic Encephalomyelitis (ME) is a multisystem, complex, acquired illness with symptoms related mainly to the dysfunction of the brain, gastro-intestinal, immune, endocrine and cardiac systems. ME has been classified as a neurological disorder in the World Health Organisation's International Classification of Diseases under Postviral Fatigue Syndrome (PVFS) since 1969 (ICD 10 G93.3). Since 1992, the term "Chronic Fatigue Syndrome" (CFS) has been included in the Alphabetical Index and indexed to G93.3
In WHO ICD 11 the classification code will be 8E49 Postviral fatigue syndrome and this includes Benign myalgic encephalomyelitis and chronic fatigue syndrome

To date there is no known specific medical diagnostic test to determine or confirm a correct diagnosis nor is there any specific treatment for this condition.

  • Myalgic Encephalomyelitis (ME) is a severe systemic, acquired illness
  • Estimated to be 2* as common as MS and 3* times more prevalent than HIV/AIDS,
  • Clear clinical symptoms which manifest predominantly based on neurological, immunological and endocrinological dysfunction
  • Multi-factorial pathogenesis with the hypothesis of initiation by a viral infection prominent.
  • Most frequently follows an acute prodromal infection, varying from upper respiratory infections, bronchitis or sinusitis, or gastroenteritis, or an acute “flu-like” illness.
  • Before acquiring ME most patients were healthy, leading full and active lifestyles.
  • Reaction to physical and mental activity and sensory input is unique to ME.
  • Over-exertion can make ME worse and the effects are often delayed and may not be seen within 24 hours.
  • Symptoms can range from mild to very severe and can include:
  • Cardiac and Cardiovascular Problems
    • Cognitive Dysfunction
    • Gastro-intestinal Problems
    • Headaches
    • Hormonal Imbalance
    • Immunological Problems
    • Muscle Weakness and Intense Pain
    • Neurological Problems
    • Sleep Problems